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Optimal high-throughput screening : practical experimental design and data analysis for genome-scale RNAi research / Xiaohua Douglas Zhang.

By: Publication details: Cambridge: Cambridge University Press, 2011.Description: xviii, 203 p. col. illISBN:
  • 9780521734448 (paperback)
Subject(s): DDC classification:
  • 615.19 Q12
Online resources:
Contents:
Machine generated contents note: Part I. RNAi HTS and Data Analysis: 1. Introduction to genome-scale RNAi research; 2. Experimental designs; 3. Data display and normalization; 4. Quality control in genome-scale RNAi screens; 5. Hit selection in genome-scale RNAi screens without replicates; 6. Hit selection in genome-scale RNAi screens with replicates; Part II. Methodological Development for Analyzing RNAi HTS Screens: 7. Statistical methods for group comparison; 8. Statistical methods for assessing the size of siRNA effects.
Summary: "This book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening experiments from a statistically sound basis"--Provided by publisher.
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Holdings
Item type Current library Call number Status Date due Barcode Item holds
Books Books Mahatma Gandhi University Library General Stacks 615.19 Q12 (Browse shelf(Opens below)) Available 56678
Total holds: 0

Includes bibliographical references (p. [189]-199) and index.

Machine generated contents note: Part I. RNAi HTS and Data Analysis: 1. Introduction to genome-scale RNAi research; 2. Experimental designs; 3. Data display and normalization; 4. Quality control in genome-scale RNAi screens; 5. Hit selection in genome-scale RNAi screens without replicates; 6. Hit selection in genome-scale RNAi screens with replicates; Part II. Methodological Development for Analyzing RNAi HTS Screens: 7. Statistical methods for group comparison; 8. Statistical methods for assessing the size of siRNA effects.

"This book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening experiments from a statistically sound basis"--Provided by publisher.

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