Optimal high-throughput screening : practical experimental design and data analysis for genome-scale RNAi research / Xiaohua Douglas Zhang.
Publication details: Cambridge: Cambridge University Press, 2011.Description: xviii, 203 p. col. illISBN:- 9780521734448 (paperback)
- 615.19 Q12
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615.19 P91 Drugs: | 615.19 Q01 Drug design : | 615.19 Q11 Wilson and Gisvold's text book of organic medicinal and pharmaceutical chemistry/ | 615.19 Q12 Optimal high-throughput screening : | 615.19 Q3 Cellular and subcellular nanotechnology : | 615.19 Q31 Formulation tools for pharmaceutical development / | 615.19 Q32 Molecular pharmacology: |
Includes bibliographical references (p. [189]-199) and index.
Machine generated contents note: Part I. RNAi HTS and Data Analysis: 1. Introduction to genome-scale RNAi research; 2. Experimental designs; 3. Data display and normalization; 4. Quality control in genome-scale RNAi screens; 5. Hit selection in genome-scale RNAi screens without replicates; 6. Hit selection in genome-scale RNAi screens with replicates; Part II. Methodological Development for Analyzing RNAi HTS Screens: 7. Statistical methods for group comparison; 8. Statistical methods for assessing the size of siRNA effects.
"This book focuses on commonly used and recently developed methods for designing and analyzing high-throughput screening experiments from a statistically sound basis"--Provided by publisher.
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