Includes bibliographical references and index.

Machine generated contents note: pt. I Fundamentals of joining and assembly in medical materials and devices -- 1.Introduction to medical materials and devices / J. J. Ramsden -- 1.1.Introduction -- 1.2.The anatomy of interaction -- 1.3.Materials for drug delivery -- 1.4.The metrology of biocompatibility -- 1.5.Conclusion -- 1.6.Future trends -- 1.7.Sources of further information -- 1.8.References -- 2.Introduction to joining methods in medical applications / L. Quintino -- 2.1.Introduction -- 2.2.Welding processes -- 2.3.Adhesive bonding -- 2.4.Examples of applications -- 2.5.References -- 3.Microwelding methods in medical components and devices / Y. Zhou -- 3.1.Introduction -- 3.2.Materials challenges -- 3.3.Medical components and devices -- 3.4.Joint design and process selection -- 3.5.Testing and verification -- 3.6.Conclusion and future trends -- 3.7.References -- 4.The effects of sterilization on medical materials and welded devices / W. J. Rogers --

Contents note continued: 4.1.Introduction to sterilization -- 4.2.Sterilization methods -- 4.3.The effects of sterilizing on different materials -- 4.4.The effects of sterilizing on welded joints -- 4.5.Selecting a suitable sterilization method -- 4.6.Conclusions -- 4.7.Sources of further information -- 4.8.References -- pt. II Joining and assembly of medical metals -- 5.Micro-welding of shape-memory alloys / Y. Zhou -- 5.1.Introduction -- 5.2.Fundamentals of Nitinol shape-memory alloys -- 5.3.Micro-welding of NiTi -- 5.4.Future trends -- 5.5.Conclusion -- 5.6.References -- 6.Joining of platinum (Pt) alloy wires to stainless steel wires for electronic medical devices / Y. Zhou -- 6.1.Introduction -- 6.2.Material properties -- 6.3.Material challenges in joining -- 6.4.The crossed-wire joint -- 6.5.Joining processes -- 6.6.Future trends -- 6.7.Conclusions -- 6.8.References -- 7.Evaluating the corrosion performance of metal medical device welds / D. F. Untereker --

Contents note continued: 7.1.Introduction -- 7.2.Measurements of corrosion -- 7.3.Direct measurements of corrosion current -- 7.4.Considerations when gathering corrosion data -- 7.5.Test sample preparation -- 7.6.Instrumentation and equipment -- 7.7.Interpretation of data -- 7.8.Mitigations for weld corrosion -- 7.9.Future trends -- 7.10.Sources of further information -- 7.11.References -- 8.Laser hermetic welding of implantable medical devices / J. Xie -- 8.1.Introduction -- 8.2.Hermetic-sealing techniques -- 8.3.Laser conduction welding -- 8.4.Focused laser beams -- 8.5.Laser welding parameters -- 8.6.Requirements for laser hermetic welds -- 8.7.Conclusion and future trends -- 8.8.References -- 9.Validating hermeticity in welded metallic implantable medical devices / K. J. Ely -- 9.1.Introduction -- 9.2.The physics of leak rates -- 9.3.Measurement of leak rates - testing and verification -- 9.4.Determining leak rate based on helium content -- 9.5.References --

Contents note continued: pt. III Joining and assembly of medical plastics -- 10.Overview of welding methods for medical plastics / H. J. Yeh -- 10.1.Introduction -- 10.2.Fundamental processes of plastics welding -- 10.3.Medical plastics and weldability -- 10.4.Part and joint design -- 10.5.Processes with external heating -- 10.6.Processes with internal heating -- 10.7.Processes with implant welding -- 10.8.Potential impacts from other manufacturing processes -- 10.9.Special applications for welding of medical plastics -- 10.10.References -- 11.Ultrasonic welding of medical plastics / H. J. Yeh -- 11.1.Introduction -- 11.2.Ultrasonic-welding processes fundamentals -- 11.3.Ultrasonic-welding process parameters and control -- 11.4.Weldability -- 11.5.Horn design -- 11.6.Part and joint design -- 11.7.Process optimization -- 11.8.Other specific applications -- 11.9.Troubleshooting -- 11.10.Advantages and limitations -- 11.11.References --

Contents note continued: 12.Radio frequency (RF)/dielectric welding of medical plastics / H. J. Yeh -- 12.1.Introduction -- 12.2.Dielectric heating fundamentals -- 12.3.Dielectric welding/sealing process description and process parameters -- 12.4.Key factors affecting the sealing process and seal quality -- 12.5.Weldability -- 12.6.Testing approaches for seals and the dielectric sealing process -- 12.7.RF welding process advantages, limitations and future trends -- 12.8.Reference -- 13.Transmission laser welding strategies for medical plastics / I. Jones -- 13.1.Introduction -- 13.2.Advantages and limitations of laser welding -- 13.3.Process description -- 13.4.Main welding parameters and effects -- 13.5.Forms of equipment -- 13.6.Weldable materials -- 13.7.Joint designs -- 13.8.Monitoring and quality control -- 13.9.Applications -- 13.10.References -- 14.Bonding strategies and adhesives for joining medical device components / T. Grailer -- 14.1.Introduction --

Contents note continued: 14.2.Designing a joint with adhesive -- 14.3.Mechanisms of adhesion -- 14.4.Adhesion promotion -- 14.5.Types of adhesives used in medical devices -- 14.6.Conclusion -- 14.7.Sources of further information and advice -- 14.8.References -- pt. IV Joining and assembly of biomaterial and tissue implants -- 15.Advanced metal-ceramic joining techniques for orthopaedic applications / G. Sala -- 15.1.Introduction -- 15.2.The challenges of joining metals to ceramics -- 15.3.Mechanical joining techniques -- 15.4.Direct and indirect bonded joining techniques -- 15.5.Active brazing joining techniques -- 15.6.Future trends -- 15.7.Sources of further information and advice -- 15.8.References -- 16.Tissue adhesives and sealants for surgical applications / A. Coury -- 16.1.Introduction -- 16.2.Principles of tissue adhesives and sealants -- 16.3.Definitions and general considerations -- 16.4.Mechanisms of bonding -- 16.5.Application methods --

Contents note continued: 16.6.Synthetic bioresorbable sealants -- 16.7.Commercial resorbable synthetic sealants and adhesives -- 16.8.Commercial resorbable bio-derived sealants and adhesives -- 16.9.Commercial biostable bio-derived sealants and adhesives -- 16.10.Commercial biostable synthetic sealants and adhesives -- 16.11.Conclusion -- 16.12.Sources of further information and advice -- 16.13.References -- 17.Antibacterial adhesives for bone and tooth repair / A. M. Young -- 17.1.Introduction to tooth repair -- 17.2.Introduction to bone repair -- 17.3.Future trends -- 17.4.Acknowledgment -- 17.5.References -- 18.Testing bond strength: the case of dental biomaterials / R. Van Noort -- 18.1.Introduction -- 18.2.Rationale for bond strength testing -- 18.3.Classification of dental adhesive testing techniques -- 18.4.Behavioural adhesive tests -- 18.5.Structural adhesive tests -- 18.6.Future trends -- 18.7.Conclusion -- 18.8.References.